A future of transplantation where
every organ counts

Woman in a mustard blazer with eyes closed, posing in profile against a plain background, representing a transplant patient.

This Changes
Wait Times

We’re the organ technology company tackling the world’s toughest transplant challenges.

Meet OrganOx

Empowering Clinicians to Save More Lives

Developed by pioneers in the fields of organ transplantation and biomedical engineering, the OrganOx metra® platform uses normothermic machine perfusion (NMP) to extend organ preservation times.

OrganOx metra normothermic machine perfusion (NMP) device for liver transplant procedures.

Longer Preservation

Extended preservation gives clinicians more options for assessing organ viability, which can reduce organ discard rates.
Lower discard rates result in shorter transplant waiting lists1 and improved outcomes2 for recipients.

Surgical team in sterile gowns and masks performing an organ transplantation surgery under overhead lights.

Preservation Times of
Up to 12 Hours*

Confident Assessment

Near-physiologic conditions enable clinicians to more accurately evaluate organ function and confidently assess viability for transplant.
Reducing uncertainty leads to more transplants and higher success rates.4

Two healthcare professionals wearing masks and gloves reviewing documents.

Perfusion at Near-Physiologic Conditions

Operational Efficacy

Keeping an organ viable outside the body longer enables transplant centers to optimize surgeries as planned, scheduled procedures. Better pre-transplant optimization may increase the likelihood of transplant success, reduce hospitalization time, and lead to fewer rehospitalizations.5

Explore OrganOx metra
Two surgeons performing an organ transplant procedure under bright surgical lights in an operating room.

Enhanced Procedural Optimization

From Preservation to Possibility

We’re looking ahead to even greater challenges and developing new technologies to help save more lives. Our organ technology is enhancing research at some of the world’s top institutions6 to treat diseased organs and develop technologies that may someday decrease the need for transplants.

Learn How
  1. Wehrle, C. J., Hong, H., Gross, A., Liu, Q., Ali, K., Cazzaniga, B., Miyazaki, Y., Tuul, M., Modaresi Esfeh, J., Khalil, M., Pita, A., Fernandes, E., Kim, J., Diago-Uso, T., Aucejo, F., Kwon, D. C. H., Fujiki, M., Quintini, C., Schlegel, A., Pinna, A., … Hashimoto, K. (2024). The impact of normothermic machine perfusion and acuity circles on waitlist time, mortality, and cost in liver transplantation: A multicenter experience. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 10.1097/LVT.0000000000000412. Advance online publication. https://doi.org/10.1097/LVT.0000000000000412
  2. Wehrle, C. J., Zhang, M., Khalil, M., Pita, A., Modaresi Esfeh, J., Diago-Uso, T., Kim, J., Aucejo, F., Kwon, D. C. H., Ali, K., Cazzaniga, B., Miyazaki, Y., Liu, Q., Fares, S., Hong, H., Tuul, M., Jiao, C., Sun, K., Fairchild, R. L., Quintini, C., … Schlegel, A. (2024). Impact of Back-to-Base Normothermic Machine Perfusion on Complications and Costs: A Multicenter, Real-World Risk-Matched Analysis. Annals of surgery, 280(2), 300–310. https://doi.org/10.1097/SLA.0000000000006291
  3. OrganOx Ltd. (2024). OrganOx® metra® instructions for use (USA version, Rev05). OrganOx Ltd. [MM1] https://sites.google.com/view/2tyshpvxatbpbjgs7bff6bs7nturpw/na-ifu?authuser=0
  4. Mergental, H., Laing, R. W., Kirkham, A. J., Perera, M. T. P. R., Boteon, Y. L., Attard, J., Barton, D., Curbishley, S., Wilkhu, M., Neil, D. A. H., Hübscher, S. G., Muiesan, P., Isaac, J. R., Roberts, K. J., Abradelo, M., Schlegel, A., Ferguson, J., Cilliers, H., Bion, J., Adams, D. H., … Mirza, D. F. (2020). Transplantation of discarded livers following viability testing with normothermic machine perfusion. Nature communications, 11(1), 2939. https://doi.org/10.1038/s41467-020-16251-3
  5. Wehrle, C. J., Zhang, M., Khalil, M., Pita, A., Modaresi Esfeh, J., Diago-Uso, T., Kim, J., Aucejo, F., Kwon, D. C. H., Ali, K., Cazzaniga, B., Miyazaki, Y., Liu, Q., Fares, S., Hong, H., Tuul, M., Jiao, C., Sun, K., Fairchild, R. L., Quintini, C., … Schlegel, A. (2024). Impact of Back-to-Base Normothermic Machine Perfusion on Complications and Costs: A Multicenter, Real-World Risk-Matched Analysis. Annals of surgery, 280(2), 300–310. https://doi.org/10.1097/SLA.0000000000006291
  6. Company data on file